The 10 Critical Elements of Server Backup Technology
by Nick Mueller, Zetta.net
VNM092712 - Local and off-site Backup Combination. It's a best practice to have a combination of local and off-site backup. Typically you want to keep large files, like databases and system state file backups on-site. This enables a quick recovery of the latest version of these files and reduces downtime. It's the most practical if your available bandwidth limits how fast you can restore these large files over the wire.
Read more at 3-in-1 Online Server Backup - Local Copy, Instant Offsite, On-Demand DR